Vibrant, Interactive, & Inclusive Department.Investigating key physiology and neurobiology questions using diverse approaches
Physiology and Neurobiology
We carry out research and education that is innovative, collaborative, and centered on cutting-edge science. We bring together researchers and educators focused on the molecular, cellular, and circuit-based mechanisms that underlie diverse functions orchestrated by the brain and body. By integrating work across the spectrum of Physiology and Neurobiology, we aim to advance our understanding of brain-body functions and interactions under normal conditions and disease.
News @ PNB
Congratulations Alix on receiving this recognition! The ASMS Graduate Student Award recognizes graduate students whose academic achievements and current mass spectrometry research display a high level of excellence and distinction. Way to go!
Super honored to receive one of the 2022 Graduate Student Travel Awards. It's been a wonderful week here in Minneapolis! #ASMS2022
A Message From The Department Head
'Welcome to the Department of Physiology and Neurobiology (PNB) website at the University of Connecticut. PNB, formerly the Physiology section of the Department of Biological Sciences, was established as a department in 1986. Today, PNB is one of the twenty-five departments in the College of Liberal Arts and Sciences. We are a vibrant, collegial, interactive, and inclusive department, housed in the Pharmacy/Biology and Torrey Life Science Buildings on the UConn Storrs main campus.
PNB is the home to twenty-two faculty members with diverse cultural and educational background who are investigating fundamental physiology and neurobiology questions using a variety of approaches. Research areas include neurobiology, reproductive biology, development, RNA processing, and human disease models, as well as research on STEM education. We also oversee the Bioscience Electron Microscopy Laboratory, which provides service and training to users across the Storrs campus.'
A Message From The Department Head
Dr. Akiko Nishiyama
'Welcome to the Department of Physiology and Neurobiology (PNB) website at the University of Connecticut. PNB, formerly the Physiology section of the Department of Biological Sciences, was established as a department in 1986. Today, PNB is one of the twenty-five departments in the College of Liberal Arts and Sciences. We are a vibrant, collegial, interactive, and inclusive department, housed in the Pharmacy/Biology and Torrey Life Science Buildings on the UConn Storrs main campus.'READ FULL MESSAGE
Histamine/H1 receptor signaling in the parafacial region increases activity of chemosensitive neurons and respiratory activity in rats
Sobrinho CR, Milla BM, Soto-Perez J, Moreira TS, Mulkey DK.
J Neurophysiol. 2022 Jun 15. doi: 10.1152/jn.00015.2022. Online ahead of print. PMID: 35704395
Removal of KCNQ2 from parvalbumin-expressing interneurons improves anti-seizure efficacy of retigabine.
Jing J, Dunbar C, Sonesra A, Chavez A, Park S, Yang R, Soh H, Lee M, Tzingounis A, Cooper EC, Jiang X, Maheshwari A.
Exp Neurol. 2022 Jun 9:114141. doi: 10.1016/j.expneurol.2022.114141. Online ahead of print.PMID: 35691372
The Okur-Chung Neurodevelopmental Syndrome Mutation CK2K198R Leads to a Rewiring of Kinase Specificity.
Caefer DM, Phan NQ, Liddle JC, Balsbaugh JL, O'Shea JP, Tzingounis AV, Schwartz D.
Front Mol Biosci. 2022 Apr 19;9:850661. doi: 10.3389/fmolb.2022.850661. eCollection 2022. PMID: 35517865
MicroRNA-200c coordinates HNF1 homeobox B and apolipoprotein O functions to modulate lipid homeostasis in alcoholic fatty liver disease.
Mostofa MG, Tran M, Gilling S, Lee G, Fraher O, Jin L, Kang H, Park YK, Lee JY, Wang L, Shin DJ.
J Biol Chem. 2022 Apr 20;298(6):101966. doi: 10.1016/j.jbc.2022.101966. Online ahead of print. PMID: 35460694
5-HT7 receptors expressed in the mouse parafacial region are not required for respiratory chemosensitivity.
Shi Y, Sobrinho CR, Soto-Perez J, Milla BM, Stornetta DS, Stornetta RL, Takakura AC, Mulkey DK, Moreira TS, Bayliss DA.
J Physiol. 2022 Jun;600(11):2789-2811. doi: 10.1113/JP282279. Epub 2022 Apr 21. PMID: 35385139
- Akiko Nishiyama Explains the Many Strengths of a PNB Degree'The new department head of physiology and neurobiology combines her background in medical training and scholarly research to lead students into the future of biomedical research.'